South Florida woman turns ALS diagnosis into mission to inspire others to fight

Surrounded by family, friends and supporters, this year’s Walk to Defeat ALS champion, Lourdes Machado, was shining with hope.

Diagnosed with ALS in May 2025, she has turned her journey into a mission to raise awareness and inspire others in the fight against the disease.

“Obviously, there’s no cure, and that’s why we’re walking,” Machado said. “We’re walking so no one else has to go through this again, and so I can spend more time with my daughter and be there for her.”

By her side through every challenge has been her mother, Marianela Perez, serving as both caregiver and unwavering source of strength.

When she first learned of her daughter’s diagnosis, Perez said she wanted her daughter to know she was not alone.

“I wanted to say I love you a lot and I’m going to be here for you and here to support you,” Perez said. “And I’ve done it for the last year, and I will continue to do it. I’m very proud of her. Very proud.”

The ALS Association is helping families like Machado’s while also investing in groundbreaking research through its partnership with the University of Miami.

Researchers are working to unlock new treatments.

Dr. Nathan Carberry, an assistant professor of neurology at the University of Miami, said scientists are seeing encouraging progress in genetic treatments that have improved patients’ strength. A development that was once thought impossible.

“I liken it to the moon landing, where we’re really seeing, finally, a true impact on a neurodegenerative disease, which is really powerful,” Carberry said.

For families facing ALS, breakthroughs like these are delivering something that once felt out of reach — hope.

The money raised through the Walk to Defeat ALS helps families access resources, support and care.

The organization welcomes support year-round.

Check out the ALS Association website to learn more about how you can get involved.

This report was produced by Miami Herald news partner CBS News Miami.