Shannen Doherty: What a trip!

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Shannen Doherty went way out of her 90210 comfort zone for her new show on Great American Country, Off The Map with Shannen & Holly. It debuts 10 p.m. Friday.

The “Holly” in the title? That would be Doherty’s onetime Charmed costar Holly Combs. The two actresses and off-set friends ventured into the Deep South for a month last summer on a road trip to remember. They were in Miami over the weekend to talk about their experiences.

“Every place was fantastic because there was so much to see and do and the people were fantastic, warm and welcoming,” said Doherty, who was born in Memphis, Tennessee. “Mississippi was awesome because the music there is just so raw and real — all blues.”

No itinerary to the South would be complete without a stop in Florida. Among the activities: entering into a fast paced high stakes poker run in Destin; flying over the Gulf waters in a tiny Cessna in search of turtles, dolphin and whale sharks; and canoeing in Grayton Beach.

“That was great — the white sandy beaches, plus the key lime martinis and key lime pie,” recalled Doherty, who has ventured into reality television before. Back in 2012, Shannen Says on WEtv documented her wedding to celebrity photographer Kurt Iswarienko. “I swam in the ocean at every chance I got, flew a plane, went on a boat, saw dolphins, went with the volunteers who protect the sea turtle nest and ate a lot of good food.”

Car travel isn’t necessarily the most glamorous, so one essential was a box of anti bacterial wipes, “because you never know,” said Doherty, who also didn’t step out of the vehicle without sunblock or an Ipad.

Any tips for folks looking to take cool, off the beaten trips?

“Don’t be afraid to explore,” Doherty advised. “Yes, you want to be safe, but ask the locals where to go and what to see. Don’t just rely on the standard travel blogs.”

The roadtripper wished she could stay longer in the Magic City.

“I used to travel to Miami all the time,” Doherty explained. “I love the coffee — the real Cuban coffee. I love eating at Casa Tua and just soaking up the energy.”