Note: All prices are subject to availability and change.

Where to stay: The Coombs House Inn. Named one of the 30 Outstanding Inns in the United States by Travel and Leisure Magazine, this 23-room mansion has become a landmark, not only for its beauty and elegance, but for its service and mouth-watering breakfasts. Rates from $89 (off-season) to $229. 80 Sixth St., Apalachicola. 888-244-8320. www.coombshouseinn.com.

Where to eat: For a town its size, Apalachicola has a number of excellent restaurants.

Caroline's combines the freshest seafood with a river view.

Avenue Sea at the Gibson Inn (reservations definitely recommended, 850-653-2193) offers the tantalizing fare of Chef David Carrier, formerly at the famed French Laundry in Napa Valley, Calif. His six-course tasting menu and wine pairing (priced at $75, eight courses for $105) boasts exotic fare such as sashimi of Cobia with bok choy and Thai peppercorns, Amish chicken with buttermilk dumplings and Swiss chard, braised octopus with chick peas, and butterscotch creme brulee with pecan sandies.

Of course, leaving Apalachicola without indulging in as many oysters as possible would be a bit like going to North Carolina and bypassing barbecue. Every restaurant has them on the menu, but one of the best places to indulge and at the same time enjoy a view of the river is Boss Oyster, which offers them more than 20 different ways.

INFO: Contact the Apalachicola Bay Chamber of Commerce at www.apalachicolabay.org or 850-653-9419.