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Florida BioTechnology News

• Scripps Florida Team Awarded $1.2 Million to Develop Drug Candidates for Rheumatoid Arthritis and Neurodegenerative Disorders

  Scripps Research scientists have been awarded approximately $1.2 million from the National Institute of General Medical Sciences of the National Institutes of Health to identify, test and develop a series of drug candidates for a number of diseases, including rheumatoid arthritis, heart disease and several neurodegenerative disorders.

  Derek R. Duckett, associate [...]

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• Dendritic cell vaccine for relapsed neuroblastoma patient induces complete remission

  One year after his last treatment, a six-year-old boy with recurrent neuroblastoma is in complete remission for his high-risk metastatic cancer. Complete Remission Following Decitabine/Dendritic Cell Vaccine for Relapsed Neuroblastoma, reported in Pediatrics, the journal of the American Academy of Pediatrics, was funded in part by a joint grant from [...]

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• First Stroke Patients in Florida Treated in UM Stem Cell Trial

  The first two stroke patients have been enrolled in a phase 2 clinical trial of a revolutionary new treatment for ischemic stroke being conducted at the University of Miami/Jackson Memorial Hospital. The trial, using a patient’s own bone marrow stem cells, is the first intra-arterial stroke stem cell trial in [...]

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• Scripps Research Institute Appoints Memory Researcher to Faculty

  The Scripps Research Institute (TSRI) has appointed Assistant Professor Seth Tomchik as a laboratory head on the Florida campus. Previously, Tomchik was a senior research associate and a member of the Ron Davis laboratory at Scripps Florida.

  “It is a genuine pleasure to welcome Seth to our faculty,” said Ronald Davis, [...]

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• Progress on the Artificial Pancreas

  Institut de recherches cliniques de Montréal researchers, led by endocrinologist Dr. Rémi Rabasa-Lhoret, were the first to conduct a trial comparing a dual-hormone artificial pancreas with conventional diabetes treatment using an insulin pump and showed improved glucose levels and lower risks of hypoglycemia. Glucose-responsive insulin and glucagon delivery (dual-hormone artificial [...]

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• BioFlorida Searches for New President, CEO

  BioFlorida is seeking a new president and CEO to direct the statewide trade association’s programs and advocacy initiatives, following the departure of former CEO Russell Allen to Georgia Bio. The BioFlorida Board of Directors’ search committee aims to fill the position by May, and the new leader will be welcomed [...]

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• Potential of differentiated iPS cells in cell therapy without immune rejection

  Lack of Immune Response to Differentiated Cells Derived from Syngeneic Induced Pluripotent Stem Cells, a new study from Boston University School of Medicine researchers, shows that tissues derived from induced pluripotent stem (iPS) cells in an experimental model were not rejected when transplanted back into genetically identical recipients. The [...]

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• Magnetic levitation makes in vitro lung tissue more realistic

  This microscopic image shows the structure and layers of in vitro bronchiole tissue created at Rice University and Nano3D Biosciences. The cell layers include epithelial cells (EpiC), smooth muscle cells (SMC), pulmonary fibroblasts (PF) and pulmonary endothelial cells (PEC).

  In a development that could lead to faster and more effective [...]

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• ‘Achilles Heel’ of Key HIV Replication Protein Found

  Researchers at the University of Pittsburgh School of Medicine may have found an “Achilles heel” in a key HIV protein. Effector Kinase Coupling Enables High-Throughput Screens for Direct HIV-1 Nef Antagonists with Antiretroviral Activity, published in Chemistry and Biology, shows that targeting this vulnerable spot could stop the virus from replicating, [...]

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• Link between inflammation and spread of breast cancer exposed

  Cancer is lethal because it spreads, or metastasizes, and curing cancer depends on knowing just how this process works. Cornell biomedical engineers have uncovered a groundbreaking link between the body’s natural inflammatory response, and how malignant breast cancer cells use the bloodstream to metastasize.

  Phenotypic Switch in Blood: Effects of [...]

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