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Florida BioTechnology News

• Mayo Clinic in Florida Recognized for Safety and as ‘Top Hospital’

  Mayo Clinic’s Jacksonville hospital is being recognized this week as one of the top hospitals in the nation by the Leapfrog Group, an independent, national nonprofit organization run by employers and other large purchasers of health benefits. Mayo Clinic is the only hospital in Northeast Florida and one [...]

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• Dr. Ted Ross Joins the Vaccine & Gene Therapy Institute of Florida as Program Director

  The Vaccine and Gene Therapy Institute of Florida has appointed Ted M. Ross, Ph.D., as Program Director. Dr. Ross will explore new vaccine technologies intended to protect against all strains of seasonal influenza. Such a vaccine could potentially eliminate the need for seasonal flu shots.

  Traditionally, the flu vaccine is [...]

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• Early Phase Trial of Gene Engineered T Cells Targeting Cancer Testis Antigens in Multiple Myeloma

  Adaptimmune today announces the release of preliminary results from an early phase clinical study using patients’ own T cells that have been genetically altered to attack multiple myeloma (MM) cells. Lead investigators for the study presented in three separate sessions at the annual meeting of the American Society of Hematology [...]

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• Toxic Interaction in Neurons that Leads to Dementia and ALS

  Mayo Clinic Florida researchers have uncovered a toxic cellular process by which a protein that maintains the health of neurons becomes deficient and can lead to dementia. The findings shed new light on the link between culprits implicated in two devastating neurological diseases: frontotemporal dementia and amyotrophic lateral sclerosis, [...]

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• Faster, safer method for producing stem cells

  A new method for generating stem cells from mature cells promises to boost stem cell production in the laboratory, helping to remove a barrier to regenerative medicine therapies that would replace damaged or unhealthy body tissues.

  The technique, developed by researchers at the Salk Institute for Biological Studies, allows for [...]

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• Immune system “kill switch” could be target for chemotherapy and infection recovery

  Researchers have discovered an immune system ‘kill switch’ that destroys blood stem cells when the body is under severe stress, such as that induced by chemotherapy and systemic infections. NLRP1 Inflammasome Activation Induces Pyroptosis of Hematopoietic Progenitor Cells is published in the journal Immunity.

  The discovery could have implications for protecting [...]

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• Engineered T cell therapy keeps Leukemia patients in remission more than 2 years

  Nine of twelve leukemia patients who received infusions of their own T cells after the cells had been genetically engineered to attack the patients’ tumors responded to the therapy, pioneered by scientists in the Perelman School of Medicine at the University of Pennsylvania.

  The clinical trial participants, all of whom had [...]

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• Mayo Clinic IDs Genes That Predict Whether Trastuzumab Will Work for Breast Cancer Patients

  Adding the drug trastuzumab to chemotherapy prevents cancer recurrence and improves survival in a large number of women with early stage HER2-positive breast cancer. But trastuzumab does not stop tumors from returning in about 25 percent of patients — and oncologists haven’t been able to identify these women before treatment. This [...]

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• Breast tumors may be biologically different in younger women

  Women with breast cancer aged 35 or younger were more likely than older women to achieve a pathological complete response after neoadjuvant chemotherapy, according to data presented at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium.

  “Young women with breast cancer are rare, and some data indicate that their prognosis is [...]

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• Predatory Open Acecess Publishers are on The Hunt

  by Mike Poller – Last night I came across an interesting list of “predatory publishers.” Each year, Jeffrey Beall, an academic librarian at the University of Colorado Denver, publishes a list of allegedly scientific journal publishers who really just want your submission fees.

  Interesting thing is, today my email [...]

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