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Florida BioTechnology News

• Scientists find Achilles’ heel of cancer cells

  Several substances inhibiting so-called HDAC enzymes have been studied in trials searching for new anti-cancer drugs in recent years. “Trials have shown that HDAC inhibitors are very effective in arresting growth of cultured cancer cells. But apart from a very rare type of lymphoma, these drugs unfortunately do not clinically [...]

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• Computers learn how to ID regulating gene sequences

  Researchers at Johns Hopkins have succeeded in teaching computers how to identify commonalities in DNA sequences known to regulate gene activity, and to then use those commonalities to predict other regulatory regions throughout the genome. The tool is expected to help scientists better understand disease risk and cell development.

  The work was reported [...]

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• First Annual Scripps Florida Mentorship Award Honors John Cleveland

  In a culture that emphasizes productivity, the value of a supportive mentor can be overlooked. Mentorship, however, is the backbone of a strong research community. That was the message of the Society of Research Fellows at Scripps Florida that recently awarded its first Mentorship Award to Professor John Cleveland.

  “We wanted [...]

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• Edith Sanford Breast Cancer Foundation and the Scripps Research Institute Partner to Advance Genomic Breast Cancer Research

  The Edith Sanford Breast Cancer Foundation and The Scripps Research Institute (TSRI) recently announced a dynamic, interdisciplinary collaboration that will lay the groundwork for significant advancements in personalized breast cancer treatment and care.

  Edith Sanford Breast Cancer Research will leverage TSRI’s expertise in genomic sequencing as it embarks on a proof-of-concept study to [...]

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• Scientists Create “Endless Supply” of Myelin-Forming Cells

  Researchers have unlocked the complex cellular mechanics that instruct specific brain cells to continue to divide. This discovery overcomes a significant technical hurdle to potential human stem cell therapies; ensuring that an abundant supply of cells is available to study and ultimately treat people with diseases. Pleiotrophin Suppression of Receptor [...]

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• Quick cook method turns algae into biofuel

  It looks like Mother Nature was wasting her time with a multimillion-year process to produce crude oil. Michigan Engineering researchers can “pressure-cook” algae for as little as a minute and transform an unprecedented 65 percent of the green slime into biocrude.

  “We’re trying to mimic the process in nature that forms [...]

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• How to unlock the destiny of a cell

  Scientists have discovered that breaking a biological signaling system in an embryo allows them to change the destiny of a cell. The findings could lead to new ways of making replacement organs.

  The discovery was made in the laboratory of Joel H. Rothman, a professor in the Department of Molecular, Cellular, [...]

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• Novel Technique To Produce Stem Cells from Peripheral Blood

  Stem cells are a valuable resource for medical and biological research, but are difficult to study due to ethical and societal barriers. However, genetically manipulated cells from adults may provide a path to study stem cells that avoid any ethical concerns.  Generation of Human Induced Pluripotent Stem Cells from [...]

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• Major flaw in standard approach to global gene expression analysis

  Whitehead Institute researchers report that common assumptions employed in the generation and interpretation of data from global gene expression analyses can lead to seriously flawed conclusions about gene activity and cell behavior in a wide range of current biological research. Revisiting Global Gene Expression Analysis is published in Cell.

  “Expression [...]

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• ALS Research and Patient Care at the Miller School Gets $1M Boost

  The ALS Recovery Fund, a steadfast ally in the fight against amyotrophic lateral sclerosis, commonly known as Lou Gehrig’s disease, has pledged another $1 million to the Department of Neurology for its continued ALS research and patient support.

  The gift will expand upon the Miller School’s existing programs and provide additional [...]

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