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Florida BioTechnology News

• Detailed views of RNA splicing

  Scientists at Yale University have described in the greatest detail yet aspects of the chemical processes by which RNA carries out the expression of our genes. Visualizing group II intron catalysis through the stages of splicing was published in Cell.

  The researchers report 14 crystal structures for a group II [...]

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• Moffitt Cancer Researchers Embark on Personalized Clinical Trial for Squamous Cell Lung Cancer

  Working with an international team of scientists, researchers at Moffitt Cancer Center have started a first-of-its-kind clinical trial for patients with squamous cell lung cancer to test a unique inhibitor drug dasatinib. The drug is aimed at DDR2, a genetic mutation found in approximately 4 percent of squamous cell [...]

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• Goodwin Biotechnology is a Three-Category Winner in the 2012 CMO Leadership Awards

  Goodwin Biotechnology, Inc. (GBI) has been named a three-category winner in the 2012 CMO Leadership Awards presented by Life Science Leader magazine. GBI was rated in the top 20% for Innovation, Productivity and Regulatory.

  “We at GBI are honored to be recognized in three categories of the CMO Leadership Awards, and [...]

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• CytoDyn Moves Corporate Headquarters to Oregon

  CytoDyn, a biotechnology company focused on the development of new therapies for combating infection with immune deficiency viruses, has relocated its corporate headquarters from Lutz, Florida to Lake Oswego, Oregon, effective immediately. The Company made the decision to relocate to Oregon because members of its new leadership team, including the [...]

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• Scientists discover potential new ‘roots’ of breast cancer

  Scientists have discovered new types of early cells in mammary glands, uncovering clues to the origins of different breast cancers, and potential new drug targets, according to findings published in Breast Cancer Research as Phenotypic and functional characterization of the luminal cell hierarchy of the mammary gland.

  The team at [...]

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• Nuclear reprogramming moves a step forward

  The idea of taking a mature cell and removing its identity (nuclear reprogramming) so that it can then become any kind of cell, holds great promise for repairing damaged tissue or replacing bone marrow after chemotherapy. Hot on the heels of his recent Nobel prize Dr. John B. Gurdon has [...]

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• UM Team Performs 100th Stem Cell Transplant

  Krishna Komanduri, M.D., the director of the Adult Stem Cell Transplant Program, and his multidisciplinary team at Sylvester Comprehensive Cancer Center performed their 100th stem cell transplant on October 26 — a historic milestone that underscores the cancer center’s growing prominence.

  Komanduri, professor of medicine, microbiology and immunology and the holder [...]

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• Nanoparticle delivery system delivers more drugs, more precisely

  A team of UC Davis scientists has shown in experimental mouse models that Tumor-targeting multifunctional micelles for imaging and chemotherapy of advanced bladder cancer allows for administration of three times the maximum tolerated dose of a standard drug therapy for advanced bladder cancer, leading to more effective cancer control without [...]

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• Mouse Model Exposes a new type of T-Cell to Target Melanoma

  Cancers arise in the body all the time. Most are nipped in the bud by the immune response, not least by its T cells, which detect telltale molecular markers—or antigens—on cancer cells and destroy them before they grow into tumors. Cancer cells, for their part, evolve constantly to evade such [...]

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• Changing a single amino acid in the TEL patch stops the growth of telomeres

  BioFrontiers Institute scientists at the University of Colorado Boulder, Tom Cech and Leslie Leinwand, have detailed a new target for anti-cancer drug development that is sitting at the ends of our DNA. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity is published in Nature.

  Researchers in [...]

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