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Florida BioTechnology News

• New method may allow personalized clinical trial for cancer therapies

  A new tool to observe cell behavior has revealed surprising clues about how cancer cells respond to therapy. Fractional proliferation: a method to deconvolve cell population dynamics from single-cell data reported in Nature Methods, may offer ways to improve personalized cancer therapy by predicting tumor response and testing combinations of [...]

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• Human embryos frozen for 18 years yield viable stem cells suitable for biomedical research

  Even after being frozen for 18 years, human embryos can be thawed, grown in the laboratory, and successfully induced to produce human embryonic stem (ES) cells, which represent a valuable resource for drug screening and medical research. Kamthorn Pruksananonda and coauthors from Chulalongkorn University and Chulalongkorn Memorial Hospital, Bangkok, Thailand, demonstrated [...]

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• Major breakthrough in hepatitis C vaccine development

  Researchers at Australia’s Burnet Institute have solved a hepatitis C vaccine mystery which, once developed could be the first ever preventative vaccine for the virus.

  Currently undergoing formal preclinical studies, the vaccine is the result of breakthrough work done by Associate Professor Heidi Drummer with her team from the Institute’s Centre [...]

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• Florida to produce bioethanol from non-food waste materials

  INEOS New Planet BioEnergy (INPB) has been granted Parts 79 and 80 registration from the U.S. EPA for the production and sale of advanced bioethanol from non-food waste materials.  The notice of registration came after the successful completion of the construction of the Indian RiverBioEnergy Center (Center) and as the facility nears production.  [...]

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• 38 new genetic regions associated with glucose and insulin levels

  Researchers have identified 38 new genetic regions that are associated with glucose and insulin levels in the blood. This brings the total number of genetic regions associated with glucose and insulin levels to 53, over half of which are associated with type 2 diabetes. Large-scale association study using the [...]

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• “Selfish” mitochondrial DNA discovered in animal for first time

  Researchers at Oregon State University have discovered, for the first time in any animal species, a type of “selfish” mitochondrial DNA that is actually hurting the organism and lessening its chance to survive – and bears a strong similarity to some damage done to human cells as they age.

  The findings, [...]

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• Hydrogels deliver sustained release of drugs for up to 6 months

  A new technology which delivers sustained release of therapeutics for up to six months could be used in conditions which require routine injections, including diabetes, certain forms of cancer and potentially HIV/AIDS.

  Researchers from the University of Cambridge have developed injectable, reformable and spreadable hydrogels which can be loaded with proteins [...]

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• Inhibiting TXNIP in people may protect their beta cells, perhaps delaying the onset of diabetes

  At its most fundamental level, diabetes is a disease characterized by stress — microscopic stress that causes inflammation and the loss of insulin production in the pancreas, and system-wide stress due to the loss of that blood-sugar-regulating hormone.

  Now, researchers led by scientists at the University of California, San Francisco (UCSF) [...]

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• Antibodies that protect against large variety of flu viruses

  A team led by scientists at The Scripps Research Institute and Crucell Vaccine Institute in the Netherlands describes three human antibodies that provide broad protection against Influenza B virus strains. The same team had previously reported finding broadly neutralizing antibodies against Influenza A strains.

  The isolation of the new broadly [...]

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• Treatment with generic vaccine kills autoimmune cells, temporarily restoring insulin production

  A phase I clinical trial has confirmed that use of a generic vaccine to raise levels of an immune system modulator can cause the death of autoimmune cells targeting the insulin-secreting cells of the pancreas and temporarily restore insulin secretion in human patients with type 1 diabetes. The study, led [...]

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