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Florida BioTechnology News

• Genetically Engineered Bacteria Prevent Mosquitoes From Transmitting Malaria

  Researchers at the Johns Hopkins Malaria Research Institute have genetically modified a bacterium commonly found in the mosquito’s midgut and found that the parasite that causes malaria in people does not survive in mosquitoes carrying the modified bacterium. The bacterium, Pantoea agglomerans, was modified to secrete proteins toxic to [...]

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• Complete Genomics Claims Long Fragment Read to Set Standard for Clinical-Grade Genomes

  Complete Genomics claims that its Long Fragment Read (LFR) technology for whole genome sequencing dramatically improves accuracy, enables fully-phased genomes, and significantly reduces the amount of DNA required for testing. LFR technology is described in this Nature paper, Accurate whole-genome sequencing and haplotyping from 10 to 20 human cells.

  “We [...]

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• Nanoscale liposomal polymeric gel drug delivery method battles cancer in mice

  Cancers are notorious for secreting chemicals that confuse the immune system and thwart the body’s natural biological defenses.

  To counter that effect, some cancer treatments attempt to neutralize the cancer’s chemical arsenal and boost a patient’s immune response, though attempts to do both at the same time are rarely successful.

  Now, researchers [...]

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• FDA creates “The 100K Genome Project” food pathogen genome database

  The U.S. Food and Drug Administration, the University of California, Davis, Agilent Technologies, and the Centers for Disease Control and Prevention announced a collaboration to create a public database of 100,000 foodborne pathogen genomes, “The 100K Genome Project,” to help speed identification of bacteria responsible for foodborne outbreaks and make [...]

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• Scripps Florida appoints Brock Grill as assistant professor

  The Scripps Research Institute has appointed Brock Grill as an assistant professor in the Department of Neuroscience. Previously, Grill was a member of the Department of Pharmacology at the University of Minnesota.

  “We’re extremely pleased to have Brock join our department,” said Ron Davis, chair of the Scripps Research Department of [...]

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• Mayo Clinic Finds Switch That Lets Early Lung Cancer Grow Unchecked

  Cellular change thought to happen only in late-stage cancers to help tumors spread also occurs in early-stage lung cancer as a way to bypass growth controls, say researchers at Mayo Clinic in Florida. The finding, reported as Matrix Metalloproteinase Induction of Rac1b, a Key Effector of Lung Cancer [...]

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• Life Sciences Banner Center offers Scripps Florida workshops on business of bioscience

  Florida’s Banner Center for Life Sciences at Palm Beach State College has entered into a year-long agreement to offer industry-driven workshops at Scripps Florida. The workshops are being presented onsite in Jupiter for Scripps Florida staff, students and faculty.

  The initial Banner Center workshops will focus on the business side of [...]

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• World’s Fastest Camera Used to Detect Rogue Cancer Cells

  The ability to distinguish and isolate rare cells from among a large population of assorted cells has become increasingly important for the early detection of disease and for monitoring disease treatments.

  Circulating cancer tumor cells are a perfect example. Typically, there are only a handful of them among a billion healthy [...]

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• Photochemically created selenium kills leukemia and solid tumor cells

  A research collaboration between the Medical College of Wisconsin (MCW) and the Children’s Research Institute in Milwaukee has found that extremely small particles of elemental selenium are highly toxic to leukemia and certain solid tumor cells but well tolerated by normal cells.  The small particles are generated when certain selenium-containing [...]

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• Positive Memories Linger Longer say Scripps Scientists

  If you believe positive reinforcement works better than the negative kind, a new study by scientists from the Florida campus of The Scripps Research Institute backs up your beliefs—at least in regard to fruit fly memory formation.

  In a new study, Distinct Traces for Appetitive versus Aversive Olfactory Memories in [...]

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