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Molecular cue that keeps quiescent stem cells from proliferating

A team led by Stowers Investigator Linheng Li, Ph.D., report that Flamingo and Frizzled 8, a tag team best known for its role in establishing cell polarity, are crucial for maintaining a quiescent reserve pool of hematopoietic stem cells in mouse bone marrow. Their finding, Noncanonical Wnt Signaling Maintains [...]

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Run entire drug discovery program from your laptop?

Assay Depot has launched a virtual research laboratory developed in partnership with AstraZeneca. The virtual laboratory is a vendor relationship management (VRM) system that gives researchers easy access to a distributed network of thousands of research service providers.

“We brought together features of today’s favorite consumer websites to create a virtual [...]

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NIH-industry collaboration will match researchers with 58 compounds to test ideas for new therapeutic uses

Five additional pharmaceutical companies have joined a National Institutes of Health-led effort to help scientists research promising new treatments for patients. Funding and molecular compound information is available now for the initial phase of the recently unveiled Discovering New Therapeutic Uses for Existing Molecules program. This NIH-industry collaboration will [...]

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