San Diego Padres (24-29) at Arizona Diamondbacks (21-33), 9:40 p.m. (ET)


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( - The San Diego Padres shoot for a series win over the Arizona Diamondbacks when the two NL West rivals tangle Wednesday night at Chase Field.

The Padres lost Monday's opener, 7-5, and returned the favor with a 4-3 victory on Tuesday. Tommy Medica's two-out solo home run in the top of the eighth inning put San Diego ahead for good and he finished 3-for-4 with two RBI.

"It was a slider down and I wasn't looking for a slider down," Medica said of his home run. "But I stayed back on it and got the barrel of the bat out front and took advantage of the Arizona air."

Cameron Maybin and Everth Cabrera had two hits apiece, as the Padres recorded their third win in the last five contests. Kevin Quackenbush, who gave up the game-winning home run on Monday, collected the win with 1 1/3 scoreless innings of relief. Huston Street logged his 15th save in the ninth.

Padres starter Eric Stults surrendered three runs on five hits and four walks over six-plus frames. He had his streak of 18 straight games of allowing two walks or less snapped.

The Padres will visit the Chicago White Sox for three games next and hope Tim Stauffer can pitch them past the D'backs. Stauffer is 2-0 with a 1.90 earned run average in 13 games (1 start) and threw five scoreless innings in Friday's 11-1 rout of the Chicago Cubs.

Stauffer hopes to make a case for a rotation spot and is 1-2 with a 1.99 ERA in 17 career games (5 starts) against Arizona.

Arizona had won three of four games until Evan Marshall served up the decisive home run in the eighth inning. Martin Prado homered for the Diamondbacks and starting pitcher Wade Miley fanned a career-high 11 batters in seven innings of three-run ball for the no-decision.

Miley allowed all three of his runs in the top of the third inning.

"I can't tell you how many times this year it's happened where we've got runs and I turn around and give some runs up," Miley said of giving up three in the third after Prado's solo homer. "You look at that, it kind of throws the momentum back their way. It hurts."

The D'backs have a four-game series with Cincinnati on the horizon and will send rookie Chase Anderson to the hill Wednesday. Anderson made his MLB debut on May 11 in a 5-1 win at the White Sox and gave up a run in 5 1/3 innings. He then pitched against the Los Angeles Dodgers on May 17 in an 18-7 rout, charged with five runs and seven hits in 5 1/3 innings.

Anderson, a right-hander, pitched against the New York Mets on Friday and hurled three shutout innings before the game was postponed by rain.

"I walked off the mound and tried to stay warm for 30 to 45 minutes, and then they cancel the game," Anderson said. "Because it didn't go five innings, it's not an official game. So it just vanishes. It's very weird."

Arizona won two of three games at San Diego earlier this month at Petco Park. The Padres are 14-10 in this series since the start of last season.

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