Maude, an Asian elephant who had been severely constipated, died at Zoo Miami on Wednesday, the second animal death at the attraction.
Maude had been unable to move her bowels for weeks, which had dangerously impacted her digestive tract and caused a loss of appetite, said spokesman Ron Magill.
Earlier this week, the zoo had consulted with some of the top veterinary experts around the country, trying to get Maude to pass the blockage through a variety of treatments including enemas, mineral oil, wheat bran, soft/wet browse and electrolyte rich fluids,
On Wednesday, Maude collapsed and died, Magill said.
Earlier in the week, a lion cub born in September died at the zoo.