"Well, you never lay it on one spot," Harbaugh said when discussing the receivers. "If we're talking offensively, precision needs to be better and that falls under everybody's purview. So, we'll try one more thing. As always, there's another thing to try and you go back to work and see if you can't improve and fix."
St. Louis has one of the game's best playmakers at cornerback in Janoris Jenkins while Cortland Finnegan is the kind of pesky veteran who can get under the opponent's skin.
"They're a good football team," Fisher said of the Niners. "What they did last year is indicative of that. You don't get to where they got last year without being able to overcome adversity. They were a few plays away from winning the world championship last year. We've got our hands full. Regardless of who's coming or who's not, they're going to be ready to play."
Defensively for San Francisco Smith is gone for now and fellow All-Pro Patrick Willis is also likely to be sidelined during the short week with a groin issue.
Smith, of course, has been one of the NFL's premier pass rushers since being taken by San Francisco with the seventh overall pick of the 2011 draft. He notched 14 sacks during his rookie season, then ranked second in the league with 19 1/2 sacks last year while helping the 49ers to an appearance in the Super Bowl. Willis is a six-time All-Pro and the leader of the San Francisco defensive unit.
Bradford has to be able to take advantage of the situation but needs some kind of running game as a complement. Starter Daryl Richardson injured his foot in the first quarter at Dallas after rushing for just 35 yards on 10 carries in Week 2. Backup Isiah Pead has shown some wiggle as a receiver but not much as a runner at his point.
"Obviously, it's very important," Rams offensive coordinator Brian Schottenheimer said when asked about sparking the run game . "I think you look at both games last year against (the 49ers), we ran the ball pretty well. It's never an easy task against them. They play with great fundamentals and technique, but we need to get the running game going."
Last year, these two teams tied in their first meeting, which took place in San Francisco, and St. Louis won the rematch on an overtime field goal by Greg Zuerlein.
For whatever reason the Rams tend to play better in divisional action (Rams QB Sam Bradford is 5-1-1 in his past seven starts against NFC West foes) and match up well with the more talented Niners. This may be an example where St. Louis was clearly looking past Dallas a week ago to this game.
"We've been on the losing end of a lot of games (in the rivalry), this organization has," Fisher said. "Now last year, we got our feet back on the map, but I don't think there's a rivalry yet. It's a division opponent. It's a big challenge for us on a short week, but I don't necessarily see it as a rivalry yet. Hopefully, we'll become one."
Sports Network Predicted Outcome: Rams 20, 49ers 17