Atlanta at New Orleans,
1 p.m., Sept. 8
Not quite the emotional landmark of 2006’s Return of The Superdome but the return of Saints coach Sean Payton after BountyGate is a big deal.
Denver at NY Giants,
4:25 p.m., Sept. 15
Especially after that rap video, can you really resist a Manning Bowl?
4:25 p.m., Sept. 22
Two of the best young quarterbacks, pocket passer Andrew Luck and pistol dual threat Colin Kapernick, slap leather.
Seattle at Houston,
1 p.m., Sept. 29
As Houston’s window on becoming Super closes, Seattle’s prying its window open.
Seattle at Indianapolis,
1 p.m., Oct. 6
Another Young Gun shootout: Russell Wilson vs. Andrew Luck.
New Orleans at
4:25 p.m., Oct. 13
The third of three consecutive games that’ll tell us how far, if at all, the Patriots have fallen.
Denver at Indianapolis,
8:30 p.m., Oct. 20
In The House Peyton Built, Peyton Manning faces the Colts for the first time.
Giants at Philadelphia,
1 p.m., Oct. 27
No list like this is complete without at least one Giants-Eagles game.
Chicago at Green Bay,
8:40 p.m., Nov. 4
A key divisional game is the NFL’s oldest rivalry on Monday Night Football. Sold.
Cincinnati at Baltimore,
1 p.m., Nov. 10
OK, Bengals, time to show the Super Bowl champs what you’ve got.
San Francisco at
4:25 p.m., Nov. 17
A rematch of the all-time classic 2011 NFC Divisional Round playoff, the last game for Sean Payton before BountyGate suspension.
8:30 p.m., Nov. 24
Peyton Manning vs. Tom Brady and maybe some Tim Tebow vs. the team that drafted him.
Pittsburgh at Baltimore,
8:30 p.m. Nov. 28
Good thing this is on Thursday. More recovery time from the NFL’s most violent rivalry.
4:25 p.m., Dec. 8
How the NFC West Was Won.
Houston at Indianapolis,
1 p.m., Dec. 15
Will a team from the Southwest or Midwest rule the AFC South?
Chicago at Philadelphia,
1 p.m., Dec. 22
Representatives of tough towns in a December game perhaps with playoff spots on the line.
Philadelphia at Dallas,
1 p.m., Dec. 29
There’s a long history of fascinating regular-season finales between these two teams.