PHOENIX -- It wasn't a banner Thursday night for the Milwaukee Brewers.

After placing leftfielder Ryan Braun on the bereavement list early in the afternoon so he could tend to a family medical situation, the Brewers opened their four-game series with the Arizona Diamondbacks with a tough-to-swallow 5-3 loss at Chase Field.

Martin Prado's two-out, bases-loaded, broken-bat single to center field off Jim Henderson was the difference in an eighth inning that saw the Brewers' setup man issue four walks (one intentional).

Following a spotty six-inning start by Yovani Gallardo and a scoreless seventh by John Axford, Henderson took the ball for the eighth and immediately found himself in trouble when he walked Adam Eaton.

Gerardo Parra moved Eaton to second with a bunt, and the Brewers followed by intentionally walking slugger Paul Goldschmidt. It was his third free pass of the night.

Henderson then struck out Aaron Hill before walking Jason Kubel to load the bases for Prado, who got ahead in the count, 2-1, before sending a 96-mph fastball from Henderson into center.

That scored Eaton and Goldschmidt and made it 5-3. Henderson issued a fourth walk, to Miguel Montero, before finally striking out Didi Gregorius to end the inning.

The Brewers got two runners on with one out in the top of the ninth against Brad Ziegler, but Logan Schafer struck out and Martin Maldonado grounded into a fielder's choice to end it.

The victory was Arizona's fourth in as many games against the Brewers this season; the Diamondbacks posted a sweep at Miller Park in April.

Gallardo was making his first start at Chase Field since March, when he helped Team Mexico to a victory over Team USA in the World Baseball Classic.

Also a reported target of the Diamondbacks in a potential trade with the deadline looming at the end of the month, Gallardo was staked to an early 2-0 lead as the Brewers came out swinging against Arizona starter Wade Miley.

Jean Segura doubled and Jonathan Lucroy followed with a two-out, two-run home run to straightaway center as Milwaukee got to the left-hander for four hits in the opening inning.

Carlos Gomez then belted his team-leading 14th homer with one out in the third, a no-doubter to left that extended the Brewers' advantage to 3-0.

While Miley was tagged for seven hits through the first three, Gallardo was cruising.

Aside from a first-inning walk issued to Goldschmidt, he didn't allow a runner to reach base while inducing six ground-ball outs.

Goldschmidt also recorded the Diamondbacks' first hit in the fourth, a single up the middle, but it wasn't until the fifth that Arizona began putting some real pressure on Gallardo.

Prado led off the frame with a double and Montero singled him to third, leaving runners on the corners with nobody out.

Gallardo struck out Gregorious before Miley followed with a bunt that moved Montero to second. With two outs and a full count, Eaton then laced a perfectly placed triple into the gap in left-center that very nearly resulted in Schafer and Gomez.

Both runners scored and it left the tying run on third for Parra, whose sharp comebacker was gloved by Gallardo to keep the Brewers in front at 3-2.

The lead didn't last long, however. Goldschmidt led off the sixth with his second walk, went to second on a wild pitch, went to third on a groundout and scored on a sacrifice fly to right by Kubel to knot it, 3-3.

Gallardo got out of the sixth with no further damage. In a 103-pitch outing, he allowed four hits, three runs (earned) and two walks to go along with three strikeouts.

As Arizona's bats heated up, Miley made sure Milwaukee's cooled off.

In fact, Miley retired 13 consecutive batters from the third to the eighth, when Norichika Aoki led off with an infield single.

Gregorious, the Diamondbacks shortstop, followed by booting a potential double-play grounder off the bat of Segura. That left him only able to force out Aoki at second.

Segura moved to second on a wild pitch as Gomez struck out but was stranded as Lucroy grounded out to second to end the inning.