In 2004 she began launching a string of Internet publications such as Consenso, Contodos and Convivencia, and later became the webmaster for Desde Cuba, a Web portal that today hosts 45 blogs, almost all critical of the Castro governments.
Three years later she launched Generación Y the first anti-government blog from inside the island and not anonymous declaring that she had tried yoga but still needed to somehow exorcize the demonic frustrations of life in Cuba.
With the government blocking access to her blog, Sánchez passed herself off as a German to use Internet cafes in tourist-only hotels and email her columns to supporters abroad who translated and posted them.
She once donned a blonde wig to slip into an academic seminar on blogging limited to government supporters.
But prestigious awards poured in for her posts. She won Columbia Universitys Maria Moors Cabot prize and Spains Ortega y Gassett award. The Prince Claus award from the Netherlands brought her $40,000. Time magazine put her on its list of 100 most influential people in 2008. And President Barack Obama answered her written questions in 2009.
The government unblocked access to Generación Y and about 40 other blogs in 2011, implicitly admitting that it could not really control what Communications Minister Ramiro Valdes called the wild pony of the Internet.
Millions of Web pages now circulate in the island on CDs, DVDs, flash drives and Bluetooth-capable cellphones. In a scene she compared to a Wild West gunfight, Sánchez wrote that people were meeting in a park, pointing their phones at each other and exchanging data without nearby police knowing what was happening.
In more recent years she has founded a bloggers academy, tweeted alerts on police arrests or harassment of other dissidents and grown more political.
Raúl Castros meek reforms are not enough to rescue the economy from its quagmire, Sánchez has declared, and once he leaves power he has promised to retire in 2018 it will be difficult for his successors to maintain control.
Cubas ruling system is like the old Havana buildings that are dilapidated yet survive even hurricanes, she told McClatchy correspondent Tim Johnson during an interview in Mexico last month.
But one day, they want to fix the door, Sánchez said. They take out screws, and the house collapses.