GAINESVILLE -- Florida will be without three players Saturday against Louisiana-Lafayette, coach Will Muschamp announced Wednesday.

Backup running back Mack Brown (ankle), wide receiver and return man Andre Debose (knee) and defensive tackle Leon Orr (flu) will not play against the Ragin’ Cajuns.

Brown injured his ankle on one of Florida’s last offensive series against Missouri last Saturday. Muschamp said Brown has not been able to practice all week.

Debose was a surprise scratch against Missouri after not being mentioned as injured all week.

Muschamp said Debose hyperextended his knee in practice last Thursday and also has not been able to practice this week.

Orr, who had to visit a local hospital last Tuesday to receive fluids through an IV as treatment for the flu, is stilling “working his way back in shape” and “probably will not play,” Muschamp said.

• Florida defensive coordinator Dan Quinn does not want to think about the prospect of losing several of his key players to the NFL Draft following the season.

According to Quinn, he’s yet to have any of those discussions with defensive end Dominique Easley, defensive tackle Sharrif Floyd, safety Matt Elam, linebacker Jelani Jenkins and cornerback Jaylen Watkins, who are all juniors and will be eligible to leave school early.

“That’s something that we haven’t talked about with them, so I certainly plan on them being here,” Quinn said. “Not a lot of discussion in that way."