The Marlins had all but given up on signing first-round draft pick Andrew Heaney. Not only had the Oklahoma State left-hander spurned their final offer of a $2.6 million signing bonus, but there was no time to get him to South Florida for a mandatory physical before Friday’s 5 p.m. deadline even if he changed his mind.

Or so they thought.

Heaney not only accepted the Marlins’ take-it-or-leave-it offer early Friday, but told the Marlins he was already in South Florida to take his physical.

“Dr. [ Lee] Kaplan and his team at the University of Miami saved the day,” said Larry Beinfest, Marlins president of baseball operations. “That’s the only way we got this thing done. They cleared out the hospital and went to the E.R. to get the blood work done, and went way above any normal timeline for a physical to get this done.”

Beinfest received the green light at 4:20 p.m. that the standout pitcher had passed his physical in order to complete the deal.

Heaney, who had been asking for the recommended slot bonus of $2.8 million as the ninth overall selection, will likely be assigned to Jamestown (N.Y.) of the short-season New York-Penn League.

Heaney went 8-2 with a 1.60 ERA for Oklahoma State last season and led the NCAA in strikeouts with 140 in 118 1/3 innings.

“This guy can move quick [up the ladder],” Beinfest said. “Ideally, for this organization, we’d love to put him right in the shadow of [ Jose] Fernandez and [ Adam] Conley and kind of click some guys through.”

Fernandez and Conley, both pitchers, were recently promoted to Single A Jupiter.

The Marlins on Friday also signed their second pick in the draft, shortstop Avery Romero, out of Pedro Menendez High in St. Augustine.

Lineup shuffle

One day after bemoaning his constant shuffling of lineups, Ozzie Guillen unveiled yet another new one on Friday by dropping Hanley Ramirez down to the fifth spot.

“I’m trying to get something going,” Guillen said. “I think right now Hanley is struggling at the plate.’’

Ramirez had never before started a game in the fifth position.

Friday also marked the return to the lineup of Emilio Bonifacio, who had been out since May 18 with a thumb injury.

Guillen used his 62nd different lineup Friday in what was the team’s 86th game.

•  Giancarlo Stanton was unable to take part in the Home Run Derby due to his knee injury. But he watched it from his hospital bed after having arthroscopic surgery Monday to remove two loose cartilage fragments from his right knee.

Stanton is expected to miss four to six weeks.

“It feels pretty good,” Stanton said Friday, the first day he was walking without crutches.

Stanton was officially placed on the 15-disabled list Friday to make room for Bonifacio.

Coming up

•  Saturday: Marlins LHP Mark Buehrle (8-8, 3.25 ERA) vs. Washington Nationals LHP Gio Gonzalez (12-3, 2.92), 7:10 p.m., Marlins Park.

•  Sunday: Marlins RHP Ricky Nolasco (8-6, 4.35) vs. Nationals RHP Stephen Strasburg (9-4, 2.82), 1:10 p.m., Marlins Park.

•  Scouting report: Hialeah product Gonzalez will be pitching in his own backyard for the first time in his major-league career on Saturday. Gonzalez, a Monsignor Pace grad who was chosen to his second consecutive All-Star team, held the Marlins to one hit over eight innings when he faced them last year in Oakland.