The main gallery of the Barnes Foundation collection is a high-ceilinged room with large windows facing south, an exact replica of the room that Dr. Albert Barnes created in Merion, Pa., to house his collection. Terese Loeb Kreuzer / Travel Arts Syndicate

The building on Benjamin Franklin Parkway housing the Barnes Foundation collection was designed by Tod Williams and Billie Tsien. Terese Loeb Kreuzer / Travel Arts Syndicate

Matisse's "Le Bonheur de Vivre," ("The Joy of Life") is a keystone painting in the Barnes collection, radical when it was painted in 1905-1906, with its exuberant colors, disjointed space and figures that are only partially defined. Terese Loeb Kreuzer / Travel Arts Syndicate

A 1926 portrait of Dr. Albert Barnes by Giorgio de Chirico. Terese Loeb Kreuzer / Travel Arts Syndicate