The second of two Princess Cruises ships that reported an outbreak of norovirus arrived Sunday morning at Port Everglades and set sail again in the afternoon — after a delay — once crews disinfected the vessel.

More than 100 passengers and crew members aboard the Ruby Princess contracted the virus, which is a highly contagious gastrointestinal illness.

“The ship was extensively disinfected including all passenger cabins and public areas, including high-touch surfaces,” Julie Benson, a spokeswoman for the cruise line, wrote in an email to The Miami Herald. “Extra cleaning crew were brought aboard and embarkation was delayed to accommodate this.”

The departure was delayed by about hour. The Ruby Princess left about 5 p.m. with some 3,100 passengers.

Previously on Saturday, a sister ship, the Crown Princess, docked at the port after a seven-day cruise. A total of 140 passengers and 18 crew members reported getting sick.

Cruise ships have struggled with containing the threat of the norovirus, which is common in the general population but which spreads more easily among large numbers of people concentrated in limited areas, like cruise ships.

The disease is passed by contact with infected people, items they touch, such as utensils or food in buffets, and human waste. Most cruise lines have hand sanitizer stations aboard, and urge passengers to use them regularly.

However, it is easy for the disease to spread even in clean environments.

After the outbreak, the cruise line sent warnings to passengers leaving Saturday and Sunday that the outbreaks would briefly delay their trips so the ships could get a stem-to-stern cleaning and disinfection.

As passengers scheduled to depart Saturday arrived, they were taken to the Broward Convention Center to await boarding. While there they were given letters explaining the illness, what was being done to clean the ship and telling them the departure would be delayed.

They were also asked to complete documents that asked whether they had any symptoms of a cold of gastrointestinal illness. Standard practice is for passengers who admit to such symptoms to be given a medical exam, and possibly be denied boarding, in an effort to prevent another outbreak.

Princess Cruises is owned by Doral-based Carnival Cruise Lines.